Blue Jays at Guardians prediction: Odds, expert picks, starting pitchers, trends, and stats for June 25
Its Wednesday, June 25 and the Blue Jays (42-36) are in Cleveland to take on the Guardians (39-38).
Max Scherzer is slated to take the mound for Toronto against Gavin Williams for Cleveland.
Toronto took the first game of this series 10-6 last night. George Springer’s grand slam in the top of the eighth inning proved to be the difference in the game. The blast was one of fourteen hits for the Jays on the night. Lane Thomas ripped a three-run shot for the Guardians in the loss.
Lets dive into the matchup and find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.
Game details & how to watch Blue Jays at Guardians
- Date: Wednesday, June 25, 2025
- Time: 6:40PM EST
- Site: Progressive Field
- City: Cleveland, OH
- Network/Streaming: Sportsnet, CLEG
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Blue Jays at the Guardians
The latest odds as of Wednesday:
- Moneyline: Blue Jays (-112), Guardians (-107)
- Spread: Blue Jays -1.5
- Total: 8.0 runs
Probable starting pitchers for Blue Jays at Guardians
- Pitching matchup for June 25, 2025: Max Scherzer vs. Gavin Williams
- Blue Jays: Max Scherzer (0-0, 6.00 ERA)
Last outing: This is Scherzer’s 1st start since being activated off the 60-day disabled list (thumb) - Guardians: Gavin Williams (5-3, 3.58 ERA)
Last outing: 6/19 at San Francisco – 6IP, 0ER, 2H, 3BB, 6Ks
- Blue Jays: Max Scherzer (0-0, 6.00 ERA)
Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!
Top betting trends & insights to know ahead of Blue Jays at Guardians
- The Blue Jays have won 4 of their last 5 on the road against American League teams
- Each of the last 3 games between the Blue Jays and the Guardians have gone over the Total
- The Blue Jays have covered the Run Line in 4 of their last 5 matchups against the Guardians
- Jose Ramirez saw his modest 5-game hitting streak snapped last night (0-5)
- Bo Bichette has hit in 4 straight games (7-20)
If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight’s game between the Blue Jays and the Guardians
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Wednesday’s game between the Blue Jays and the Guardians:
- Moneyline: NBC Sports Bet is recommending a play on the Toronto Blue Jays on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Cleveland Guardians at +1.5.
- Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
Follow our experts on socials to keep up with all the latest content from the staff:
- Jay Croucher (@croucherJD)
- Drew Dinsick (@whale_capper)
- Vaughn Dalzell (@VmoneySports)
- Brad Thomas (@MrBradThomas)
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